L R Pohl

Metabolic basis for a drug hypersensitivity: antibodies in sera from patients with halothane hepatitis recognize liver neoantigens that contain the trifluoroacetyl group derived from halothane.

J G Kenna, Hiroaki Satoh, David D. Christ et al. · Journal of Pharmacology and Experimental Therapeutics · 1988 · 211 citations

Human anti-endoplasmic reticulum antibodies in sera of patients with halothane-induced hepatitis are directed against a trifluoroacetylated carboxylesterase.

Hiroaki Satoh, Brian M. Martin, A H Schulick et al. · Proceedings of the National Academy of Sciences · 1989 · 137 citations · Full text

Immunology, Halothane-treated Rats, Pathology +19

The formation of diglutathionyl dithiocarbonate as a metabolite of chloroform, bromotrichloromethane, and carbon tetrachloride.

L R Pohl, Richard V. Branchflower, R. J. Highet et al. · Drug Metabolism and Disposition · 1981 · 102 citations

3-(glutathion-S-yl)acetaminophen: a biliary metabolite of acetaminophen.

J. A. Hinson, T J Monks, Mo Hong et al. · Drug Metabolism and Disposition · 1982 · 93 citations

Molecular Pharmacology, Biochemistry, Medicine +5

Potential metabolic basis for enflurane hepatitis and the apparent cross-sensitization between enflurane and halothane.

David D. Christ, Hiroaki Satoh, J G Kenna et al. · Drug Metabolism and Disposition · 1988 · 78 citations