J G Kenna

Metabolic basis for a drug hypersensitivity: antibodies in sera from patients with halothane hepatitis recognize liver neoantigens that contain the trifluoroacetyl group derived from halothane.

J G Kenna, Hiroaki Satoh, David D. Christ et al. · Journal of Pharmacology and Experimental Therapeutics · 1988 · 211 citations

Cytochrome P450 2E1 is a cell surface autoantigen in halothane hepatitis.

Erik Eliasson, J G Kenna · Molecular Pharmacology · 1996 · 170 citations

Human anti-endoplasmic reticulum antibodies in sera of patients with halothane-induced hepatitis are directed against a trifluoroacetylated carboxylesterase.

Hiroaki Satoh, Brian M. Martin, A H Schulick et al. · Proceedings of the National Academy of Sciences · 1989 · 137 citations · Full text

Immunology, Halothane-treated Rats, Pathology +19

Enflurane Metabolism Produces Covalently Bound Liver Adducts Recognized by Antibodies from Patients with Halothane Hepatitis

David D. Christ, J G Kenna, William Hammerer et al. · Anesthesiology · 1988 · 115 citations · Full text

Immunology, Halothane-treated Rats, Pathology +21

Antibody Assays for the Detection of Patients Sensitized to Halothane

Jackie L. Martin, J G Kenna, Lance R. Pohl · Anesthesia & Analgesia · 1990 · 85 citations

Immunology, Halothane-treated Rats, Pathology +23