The activated conformation of integrin β7 is a novel multiple myeloma–specific target for CAR T cell therapy

Naoki Hosen, Yukiko Matsunaga, Kana Hasegawa, +30

Nature Medicine

Cancer ImmunosurveillanceImmunologyCellular Immune ResponseIntegrin β7Immunotherapy +3

Retroviral vector‐producing mesenchymal stem cells for targeted suicide cancer gene therapy

Ryosuke Uchibori, Takashi Okada, Takayuki Ito, +4

The Journal of Gene Medicine

Interleukin-10 Expression Mediated by an Adeno-Associated Virus Vector Prevents Monocrotaline-Induced Pulmonary Arterial Hypertension in Rats

Takayuki Ito, Takashi Okada, Hiroshi Miyashita, +11

Circulation Research

InflammationHypertensionPulmonary Arterial HypertensionPulmonary CirculationMedicine +12

Scalable Purification of Adeno-associated Virus Serotype 1 (AAV1) and AAV8 Vectors, Using Dual Ion-Exchange Adsorptive Membranes

Takashi Okada, Mutsuko Nonaka‐Sarukawa, Ryosuke Uchibori, +5

Human Gene Therapy

BiomanufacturingEngineeringMolecular VirologySynthetic VirologyBiotechnology +10

The NOTCH–FOXM1 Axis Plays a Key Role in Mitochondrial Biogenesis in the Induction of Human Stem Cell Memory–like CAR-T Cells

Taisuke Kondo, Makoto Ando, Nao Nagai, +14

Cancer Research

NF-κB Activity Regulates Mesenchymal Stem Cell Accumulation at Tumor Sites

Ryosuke Uchibori, Tomonori Tsukahara, Hiroyuki Mizuguchi, +5

Cancer Research

Characterization of a novel oncogenic K-ras mutation in colon cancer

Kiwamu Akagi, Ryosuke Uchibori, Kensei Yamaguchi, +3

Biochemical and Biophysical Research Communications

OncologyOncogenic AgentMedicinePathologyColorectal Cancer +7

A Histone Deacetylase Inhibitor Enhances Recombinant Adeno-associated Virus-Mediated Gene Expression in Tumor Cells

Takashi Okada, Ryosuke Uchibori, Mayumi Iwata-Okada, +9

Molecular Therapy

Large-Scale Production of Recombinant Viruses by Use of a Large Culture Vessel with Active Gassing

Takashi Okada, Tatsuya Nomoto, Toru Yoshioka, +9

Human Gene Therapy

Viral ReplicationEngineeringSynthetic VirologyBiomedical EngineeringVirus Transmission +16

AAV6-Mediated IL-10 Expression in the Lung Ameliorates Bleomycin-Induced Pulmonary Fibrosis in Mice

Fumio Kurosaki, Ryosuke Uchibori, Yoshihide Sehara, +5

Human Gene Therapy

Acute Lung InjuryInflammatory Lung DiseaseLung InflammationImmunologyImmune Regulation +21