Jun‐ichiro Inoue

Induction and Activation of the Transcription Factor NFATc1 (NFAT2) Integrate RANKL Signaling in Terminal Differentiation of Osteoclasts

Hiroshi Takayanagi, Sunhwa Kim, Takako Koga et al. · Developmental Cell · 2002 · 2.6K citations · Full text

Terminal Differentiation, Integrate Rankl Signaling, Developmental Biology +11

TAK1 is a ubiquitin-dependent kinase of MKK and IKK

Chen Wang, Li Deng, Mei Hong et al. · Nature · 2001 · 2.1K citations

Signal Transduction, Signaling Pathway, Cell Regulation +6

The kinase TAK1 can activate the NIK-IκB as well as the MAP kinase cascade in the IL-1 signalling pathway

Jun Ninomiya‐Tsuji, Kazuya Kishimoto, Atsushi Hiyama et al. · Nature · 1999 · 1.2K citations

Inflammation, Cytokine, Il-1 Signalling Pathway +13

Lipopolysaccharide Stimulates the MyD88-Independent Pathway and Results in Activation of IFN-Regulatory Factor 3 and the Expression of a Subset of Lipopolysaccharide-Inducible Genes

Taro Kawai, Osamu Takeuchi, Takashi Fujita et al. · The Journal of Immunology · 2001 · 1.1K citations · Full text

Interferon-α induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6

Taro Kawai, Shintaro Sato, Ken J. Ishii et al. · Nature Immunology · 2004 · 1K citations

Inflammation, Toll-like Receptors, Molecular Immunology +14