Rakki P. Alexander

The inhibition of antigen‐induced eosinophilia and bronchoconstriction by CDP840, a novel stereo‐selective inhibitor of phosphodiesterase type 4

B. Hughes, D. Howat, H. Lisle et al. · British Journal of Pharmacology · 1996 · 95 citations · Full text

Inflammation, Molecular Pharmacology, Potent Pde 4 +12

CDP840. A prototype of a novel class of orally active anti-Inflammatory phosphodiesterase 4 inhibitors

Rakki P. Alexander, Graham J. Warrellow, Michael A. W. Eaton et al. · Bioorganic & Medicinal Chemistry Letters · 2002 · 57 citations · Full text

A Prototype, Medicine, Immunology +8

Investigation of the in vitro metabolism profile of a phosphodiesterase-IV inhibitor, CDP-840: leading to structural optimization.

Chun Li, Nathalie Chauret, Laird A. Trimble et al. · PubMed · 2001 · 21 citations

Vitro Metabolism Profile, Lipid Peroxidation, Metabolomic Profiling +26