Laird A. Trimble

Amination of chiral enolates by dialkyl azodiformates. Synthesis of .alpha.-hydrazino acids and .alpha.-amino acids

Laird A. Trimble, John C. Vederas · Journal of the American Chemical Society · 1986 · 217 citations

Natural Sciences, Chemistry, Medicinal Chemistry +11

Discovery of a Potent and Selective Prostaglandin D₂ Receptor Antagonist, [(3<i>R</i>)-4-(4-Chloro- benzyl)-7-fluoro-5-(methylsulfonyl)-1,2,3,4-tetrahydrocyclopenta[<i>b</i>]indol-3-yl]-acetic Acid (MK-0524)

Claudio F. Sturino, Gary P. O’Neill, Nicolas Lachance et al. · Journal of Medicinal Chemistry · 2007 · 170 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +8

γ-Aminobutyric Acid Type B Receptors with Specific Heterodimer Composition and Postsynaptic Actions in Hippocampal Neurons Are Targets of Anticonvulsant Gabapentin Action

Gordon Ng, Sandrine S. Bertrand, Richard Sullivan et al. · Molecular Pharmacology · 2001 · 143 citations

Life Sciences, Neuroscience, Pharmacology +17

NMR structural studies of the tight complex between a trifluoromethyl ketone inhibitor and the 85-kDa human phospholipase A2

Laird A. Trimble, Ian P. Street, Hélène Perrier et al. · Biochemistry · 1993 · 102 citations

Life Sciences, Medicinal Chemistry, Pharmacology +9

Lactate editing by means of selective-pulse filtering of both zero-and double-quantum coherence signals

Laird A. Trimble, Jie Shen, Alan H. Wilman et al. · Journal of Magnetic Resonance (1969) · 1990 · 71 citations

Natural Sciences, Physics, Quantum Mechanics +4