Rachel A. Silverstein

Patient-Specific In Vivo Gene Editing to Treat a Rare Genetic Disease

Kiran Musunuru, Sarah Grandinette, Xiao Wang et al. · New England Journal of Medicine · 2025 · 179 citations · Full text

Genetic Diseases, Genome Surgery, In Vivo Gene Therapy +15

PAM-flexible genome editing with an engineered chimeric Cas9

Lin Zhao, Sabrina Koseki, Rachel A. Silverstein et al. · Nature Communications · 2023 · 52 citations · Full text

Precise DNA cleavage using CRISPR-SpRYgests

Kathleen A. Christie, Jimmy A. Guo, Rachel A. Silverstein et al. · Nature Biotechnology · 2022 · 50 citations · Full text

Precise Dna Cleavage, Genetics, Molecular Biology +5

Custom CRISPR–Cas9 PAM variants via scalable engineering and machine learning

Rachel A. Silverstein, Nahye Kim, Ann-Sophie Kroell et al. · Nature · 2025 · 38 citations · Full text

Evolution of CRISPR-associated endonucleases as inferred from resurrected proteins

Borja Alonso-Lerma, Ylenia Jabalera, Sara Samperio et al. · Nature Microbiology · 2023 · 28 citations · Full text

Resurrected Proteins, Natural Sciences, Genetics +8