Melissa G. Dominguez

Targeted disruption of the mouse colony-stimulating factor 1 receptor gene results in osteopetrosis, mononuclear phagocyte deficiency, increased primitive progenitor cell frequencies, and reproductive defects

Xuming Dai, Gregory R. Ryan, Andrew J. Hapel et al. · Blood · 2002 · 1.1K citations · Full text

Haploinsufficiency of delta-like 4 ligand results in embryonic lethality due to major defects in arterial and vascular development

Nicholas W. Gale, Melissa G. Dominguez, Irene Noguera et al. · Proceedings of the National Academy of Sciences · 2004 · 595 citations · Full text

Developmental Biology, Angiogenesis, Embryonic Lethality +12

High-throughput engineering of the mouse genome coupled with high-resolution expression analysis

David M. Valenzuela, Andrew Murphy, David Frendewey et al. · Nature Biotechnology · 2003 · 585 citations

Engineering, Transgenic Mouse Models, Molecular Biology +17

Role of colony stimulating factor-1 in the establishment and regulation of tissue macrophages during postnatal development of the mouse

Marco Cecchini, Melissa G. Dominguez, Simonetta Mocci et al. · Development · 1994 · 561 citations

F0 generation mice fully derived from gene-targeted embryonic stem cells allowing immediate phenotypic analyses

William Poueymirou, Wojtek Auerbach, David Frendewey et al. · Nature Biotechnology · 2006 · 236 citations · Full text

Conventional Injections, Transgenic Mouse Models, Genetics +18