Melissa G. Dominguez

Targeted disruption of the mouse colony-stimulating factor 1 receptor gene results in osteopetrosis, mononuclear phagocyte deficiency, increased primitive progenitor cell frequencies, and reproductive defects

Gregory R. Ryan, Andrew J. Hapel, Melissa G. Dominguez et al. · Blood · 2002 · 1.2K citations · Full text

Life Sciences, Genetics, Molecular Genetics +14

Haploinsufficiency of delta-like 4 ligand results in embryonic lethality due to major defects in arterial and vascular development

Nicholas W. Gale, Melissa G. Dominguez, Irene Noguera et al. · Proceedings of the National Academy of Sciences · 2004 · 597 citations · Full text

Life Sciences, Developmental Biology, Genetics +17

High-throughput engineering of the mouse genome coupled with high-resolution expression analysis

David M. Valenzuela, Andrew Murphy, David Frendewey et al. · Nature Biotechnology · 2003 · 593 citations

Life Sciences, Genetics, Molecular Biology +16

Role of colony stimulating factor-1 in the establishment and regulation of tissue macrophages during postnatal development of the mouse

Marco Cecchini, Melissa G. Dominguez, Simonetta Mocci et al. · Development · 1994 · 565 citations

Life Sciences, Cell Biology, Immunology +13

F0 generation mice fully derived from gene-targeted embryonic stem cells allowing immediate phenotypic analyses

William Poueymirou, Wojtek Auerbach, David Frendewey et al. · Nature Biotechnology · 2006 · 241 citations · Full text

Life Sciences, Developmental Biology, Genetics +14