Cédric Lecoutey

Design of donecopride, a dual serotonin subtype 4 receptor agonist/acetylcholinesterase inhibitor with potential interest for Alzheimer's disease treatment

Cédric Lecoutey, Damien Hédou, Thomas Fréret et al. · Proceedings of the National Academy of Sciences · 2014 · 119 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Novel Multitarget-Directed Ligands (MTDLs) with Acetylcholinesterase (AChE) Inhibitory and Serotonergic Subtype 4 Receptor (5-HT₄R) Agonist Activities As Potential Agents against Alzheimer’s Disease: The Design of Donecopride

Christophe Rochais, Cédric Lecoutey, Florence Gaven et al. · Journal of Medicinal Chemistry · 2015 · 117 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Novel multitarget-directed ligands targeting acetylcholinesterase and σ1 receptors as lead compounds for treatment of Alzheimer's disease: Synthesis, evaluation, and structural characterization of their complexes with acetylcholinesterase

Julien Lalut, Gianluca Santoni, Delphine Karila et al. · European Journal of Medicinal Chemistry · 2018 · 50 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

The design of donecopride, a dual 5-HT4R agonist/AChE inhibitor with potential interest for AD treatment

Cédric Lecoutey, Damien Hédou, Thomas Fréret et al. · HAL (Le Centre pour la Communication Scientifique Directe) · 2014 · 39 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17

Rational design of novel benzisoxazole derivatives with acetylcholinesterase inhibitory and serotoninergic 5-HT4 receptors activities for the treatment of Alzheimer’s disease

Julien Lalut, Hugo Payan, Audrey Davis et al. · Scientific Reports · 2020 · 36 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17