Christophe Rochais

Design of donecopride, a dual serotonin subtype 4 receptor agonist/acetylcholinesterase inhibitor with potential interest for Alzheimer's disease treatment

Cédric Lecoutey, Damien Hédou, Thomas Fréret et al. · Proceedings of the National Academy of Sciences · 2014 · 119 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Novel Multitarget-Directed Ligands (MTDLs) with Acetylcholinesterase (AChE) Inhibitory and Serotonergic Subtype 4 Receptor (5-HT₄R) Agonist Activities As Potential Agents against Alzheimer’s Disease: The Design of Donecopride

Christophe Rochais, Cédric Lecoutey, Florence Gaven et al. · Journal of Medicinal Chemistry · 2015 · 117 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Pharmacotechnical Development of a Nasal Drug Delivery Composite Nanosystem Intended for Alzheimer’s Disease Treatment

Thomas Adnet, Anne‐Claire Groo, Céline Picard et al. · Pharmaceutics · 2020 · 76 citations · Full text

Pharmacy, Pharmaceutics, Pharmacology +17

Synthesis and biological evaluation of novel pyrrolopyrrolizinones as anticancer agents

Christophe Rochais, Vincent Lisowski, Patrick Dallemagne et al. · Bioorganic & Medicinal Chemistry · 2006 · 63 citations

Pharmacy, Medicinal Chemistry, Oncology +16

Novel multitarget-directed ligands targeting acetylcholinesterase and σ1 receptors as lead compounds for treatment of Alzheimer's disease: Synthesis, evaluation, and structural characterization of their complexes with acetylcholinesterase

Julien Lalut, Gianluca Santoni, Delphine Karila et al. · European Journal of Medicinal Chemistry · 2018 · 50 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17