The nuclear receptor PPARγ selectively inhibits Th17 differentiation in a T cell–intrinsic fashion and suppresses CNS autoimmunity

Luisa Klotz, Sven Burgdorf, Indra Dani, +16

The Journal of Experimental Medicine

Sodium chloride promotes pro-inflammatory macrophage polarization thereby aggravating CNS autoimmunity

Stephanie Hucke, Melanie Eschborn, Marie Liebmann, +9

Journal of Autoimmunity

InflammationSodium ChlorideCytokineAutoimmune DiseaseMedicine +10

Nur77 serves as a molecular brake of the metabolic switch during T cell activation to restrict autoimmunity

Marie Liebmann, Stephanie Hucke, Kathrin Koch, +17

Proceedings of the National Academy of Sciences

Fingolimod treatment promotes regulatory phenotype and function of B cells

Berit Grützke, Stephanie Hucke, Catharina C. Groß, +7

Annals of Clinical and Translational Neurology

Salt-Dependent Chemotaxis of Macrophages

Silke Müller, Thomas Quast, Agnes Schröder, +6

PLoS ONE

ImmunologyImmunologic MechanismImmune SystemCellular PhysiologyInflammation +15

Targeting Different Monocyte/Macrophage Subsets Has No Impact on Outcome in Experimental Stroke

Antje Schmidt, Jan‐Kolja Strecker, Stephanie Hucke, +8

Stroke

Licensing of myeloid cells promotes central nervous system autoimmunity and is controlled by peroxisome proliferator-activated receptor γ

Stephanie Hucke, Juliane Floßdorf, Berit Grützke, +14

Brain

Liver X receptor activation promotes differentiation of regulatory T cells

Martin Herold, Johanna Breuer, Stephanie Hucke, +4

PLoS ONE

Lymphocyte DevelopmentT-regulatory CellImmunologyImmune RegulationRegulatory T Cells +18

Dietary conjugated linoleic acid links reduced intestinal inflammation to amelioration of CNS autoimmunity

Ann-Katrin Fleck, Stephanie Hucke, Flavio Teipel, +20

Brain

Intestinal InflammationImmunologyInflammationConjugated Linoleic AcidGut-organ Axis +15

Increased Antigen Cross-Presentation but Impaired Cross-Priming after Activation of Peroxisome Proliferator-Activated Receptor γ Is Mediated by Up-Regulation of B7H1

Luisa Klotz, Stephanie Hucke, Dominik Thimm, +8

The Journal of Immunology

Impaired Cross-primingImmune RegulationImmunologyImmunologic MechanismAntigen Processing +19