Holger Paulsen

Dysregulation of bacterial proteolytic machinery by a new class of antibiotics

Heike Brötz‐Oesterhelt, D. Beyer, Hein‐Peter Kroll et al. · Nature Medicine · 2005 · 512 citations

Life Sciences, Microbiology, Molecular Biology +13

Discovery of BAY 94‐8862: A Nonsteroidal Antagonist of the Mineralocorticoid Receptor for the Treatment of Cardiorenal Diseases

Lars Bärfacker, Alexander Kühl, Alexander Hillisch et al. · ChemMedChem · 2012 · 264 citations

Pharmacy, Medicinal Chemistry, Pharmacology +14

Structures of ClpP in complex with acyldepsipeptide antibiotics reveal its activation mechanism

Byung‐Gil Lee, Eun Young Park, Kyung-Eun Lee et al. · Nature Structural & Molecular Biology · 2010 · 233 citations

Life Sciences, Biochemistry, Pharmacology +13

The Pinene Path to Taxanes. 5. Stereocontrolled Synthesis of a Versatile Taxane Precursor

Paul A. Wender, Neil F. Badham, Simon P. Conway et al. · Journal of the American Chemical Society · 1997 · 172 citations

Natural Sciences, Chemistry, Drug Discovery +5

Medicinal Chemistry Optimization of Acyldepsipeptides of the Enopeptin Class Antibiotics

Berthold Hinzen, Siegfried Raddatz, Holger Paulsen et al. · ChemMedChem · 2006 · 89 citations

Pharmacy, Infectious Diseases, Medicinal Chemistry +16