Holger Paulsen

Dysregulation of bacterial proteolytic machinery by a new class of antibiotics

Heike Brötz‐Oesterhelt, D. Beyer, Hein‐Peter Kroll et al. · Nature Medicine · 2005 · 504 citations

Antimicrobial Susceptibility, Health Sciences, Antibiotics +9

Discovery of BAY 94‐8862: A Nonsteroidal Antagonist of the Mineralocorticoid Receptor for the Treatment of Cardiorenal Diseases

Lars Bärfacker, Alexander Kühl, Alexander Hillisch et al. · ChemMedChem · 2012 · 255 citations

Structures of ClpP in complex with acyldepsipeptide antibiotics reveal its activation mechanism

Byung‐Gil Lee, Eun Young Park, Kyung-Eun Lee et al. · Nature Structural & Molecular Biology · 2010 · 229 citations

Proteinlipid Interaction, Biochemistry, Natural Sciences +5

The Pinene Path to Taxanes. 5. Stereocontrolled Synthesis of a Versatile Taxane Precursor

Paul A. Wender, Neil F. Badham, Simon P. Conway et al. · Journal of the American Chemical Society · 1997 · 172 citations

Biology, Pinene Path, Engineering +12

Medicinal Chemistry Optimization of Acyldepsipeptides of the Enopeptin Class Antibiotics

Berthold Hinzen, Siegfried Raddatz, Holger Paulsen et al. · ChemMedChem · 2006 · 87 citations

Global Spread, Medicinal Chemistry Optimization, Antimicrobial Chemotherapy +20