Xavier Coumoul

RNA interference and inhibition of MEK-ERK signaling prevent abnormal skeletal phenotypes in a mouse model of craniosynostosis

Vivek Shukla, Xavier Coumoul, Rui-Hong Wang et al. · Nature Genetics · 2007 · 200 citations

Sclerostin, Developmental Biology, Signaling Pathway +8

ATM–Chk2–p53 activation prevents tumorigenesis at an expense of organ homeostasis upon Brca1 deficiency

Liu Cao, Sang Soo Kim, Cuiying Xiao et al. · The EMBO Journal · 2006 · 162 citations · Full text

Tumor Biology, Cell Regulation, Organ Homeostasis +11

Activation of the dioxin/aryl hydrocarbon receptor (AhR) modulates cell plasticity through a JNK-dependent mechanism

Monique Diry, Céline Tomkiewicz, C Koehle et al. · Oncogene · 2006 · 141 citations · Full text

Reductive Stress, Lineage Plasticity, Jnk-dependent Mechanism +12

Butyrate elicits a metabolic switch in human colon cancer cells by targeting the pyruvate dehydrogenase complex

Jean‐Marc Blouin, Graziella Penot, Martine Collinet et al. · International Journal of Cancer · 2010 · 125 citations · Full text

Chemoprevention Strategy, Glycobiology, Metabolic Remodeling +20

Aryl Hydrocarbon Receptor–Dependent Induction of Liver Fibrosis by Dioxin

Stéphane Pierre, Aline Chevallier, Fatima Teixeira-Clerc et al. · Toxicological Sciences · 2013 · 118 citations · Full text

Liver Fibrosis, Immunology, Pathology +23