Xenobiotic-Metabolizing Enzymes and Transporters in the Normal Human Brain: Regional and Cellular Mapping as a Basis for Putative Roles in Cerebral Function

Fabien Dutheil, Sandrine Dauchy, Monique Diry, +11

Drug Metabolism and Disposition

Activation of the dioxin/aryl hydrocarbon receptor (AhR) modulates cell plasticity through a JNK-dependent mechanism

Monique Diry, Céline Tomkiewicz, C Koehle, +4

Oncogene

Reductive StressLineage PlasticityJnk-dependent MechanismSignal TransductionSignaling Pathway +10

A case of mitochondrial encephalomyopathy associated with a muscle coenzyme Q10 deficiency

Eric Boitier, Françoise Degoul, Isabelle Desguerre, +6

Journal of the Neurological Sciences

Mitochondrial MyopathyMitochondrial FunctionPhysiologyPathologyDegenerative Disease +4

PXR-dependent induction of human CYP3A4 gene expression by organochlorine pesticides

Xavier Coumoul, Monique Diry, Robert Barouki

Biochemical Pharmacology

BiochemistryNatural SciencesMedicineOrganochlorine PesticidesMolecular Biology +3

Differential regulation of cytochrome P450 1A1 and 1B1 by a combination of dioxin and pesticides in the breast tumor cell line MCF-7.

Xavier Coumoul, Monique Diry, C Robillot, +1

PubMed

Breast OncologyCytochrome P450 1A1Xenoestrogenic ActivityCancer BiologyTumor Biology +18

Nedd9/Hef1/Cas-L mediates the effects of environmental pollutants on cell migration and plasticity

Linh‐Chi Bui, Céline Tomkiewicz, Aline Chevallier, +10

Oncogene

Environmental SignalingHuman CellLineage PlasticityCell RegulationEnvironmental Pollutants +5

Biochemical and genetic studies of four patients with pyruvate dehydrogenase E1α deficiency

C. Marsac, Chantal Benelli, Isabelle Desguerre, +9

Human Genetics

Metabolic DisorderBiochemistryGenetic DisorderGeneticsPhysiology +5

Improvement of Cyclophosphamide Activation by CYP2B6 Mutants: From in Silico to ex Vivo

Thiên-Ân Nguyen, Marina Tychopoulos, F. Bichât, +8

Molecular Pharmacology

El Pyruvate Dehydrogenase Deficiency in a Child with Motor Neuropathy

Gisèle Bonne, Chantal Benelli, Linda De Meırleır, +8

Pediatric Research

NeurophysiologyNeurological DisorderMotor DevelopmentPhysiologyInherited Metabolic Disease +8

A near homoplasmic T8993G mtDNA mutation in a patient with atypic Leigh syndrome not present in the mother's tissues

Françoise Degoul, D. François, Monique Diry, +5

Journal of Inherited Metabolic Disease