Kimberly T. Barrett

Spontaneous transfer of chirality in an atropisomerically enriched two-axis system

Kimberly T. Barrett, Anthony J. Metrano, Paul R. Rablen et al. · Nature · 2014 · 182 citations · Full text

Biophysics, Physics, Spontaneous Transfer

Enantioselective Synthesis of Atropisomeric Benzamides through Peptide-Catalyzed Bromination

Kimberly T. Barrett, Scott J. Miller · Journal of the American Chemical Society · 2013 · 152 citations · Full text

Nonpeptidic Tetrafluorophenoxymethyl Ketone Cruzain Inhibitors as Promising New Leads for Chagas Disease Chemotherapy

Katrien Brak, Iain Kerr, Kimberly T. Barrett et al. · Journal of Medicinal Chemistry · 2010 · 132 citations · Full text

Bioorganic Chemistry, Pathology, Cell Culture +21

Prodrugs of a 1′-CN-4-Aza-7,9-dideazaadenosine <i>C</i>-Nucleoside Leading to the Discovery of Remdesivir (GS-5734) as a Potent Inhibitor of Respiratory Syncytial Virus with Efficacy in the African Green Monkey Model of RSV

Richard L. Mackman, Hon C. Hui, Michel Perron et al. · Journal of Medicinal Chemistry · 2021 · 79 citations · Full text

Therapeutic treatment with an oral prodrug of the remdesivir parental nucleoside is protective against SARS-CoV-2 pathogenesis in mice

Alexandra Schäfer, David R. Martinez, John J. Won et al. · Science Translational Medicine · 2022 · 77 citations · Full text

Immunology, Immunotherapeutics, Innate Immunity +20