Alessandra Zarantonello

Structural Investigations of Human A2M Identify a Hollow Native Conformation That Underlies Its Distinctive Protease-Trapping Mechanism

Seandean L. Harwood, Jeppe Lyngsø, Alessandra Zarantonello et al. · Molecular & Cellular Proteomics · 2021 · 37 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Functional and Structural Characterization of a Potent C1q Inhibitor Targeting the Classical Pathway of the Complement System

N.S. Laursen, Dennis Pedersen, Heidi Gytz et al. · Frontiers in Immunology · 2020 · 36 citations · Full text

Life Sciences, Immunology, Molecular Biology +17

Heme Interferes With Complement Factor I-Dependent Regulation by Enhancing Alternative Pathway Activation

Alexandra Gerogianni, Jordan D. Dimitrov, Alessandra Zarantonello et al. · Frontiers in Immunology · 2022 · 25 citations · Full text

Life Sciences, Hematology, Immunology +15

A Complement C3–Specific Nanobody for Modulation of the Alternative Cascade Identifies the C-Terminal Domain of C3b as Functional in C5 Convertase Activity

Henrik Pedersen, Rasmus K. Jensen, Jens Magnus Bernth Jensen et al. · The Journal of Immunology · 2020 · 24 citations

Life Sciences, Immunology, Molecular Biology +17

An Ultrahigh-Affinity Complement C4b-Specific Nanobody Inhibits In Vivo Assembly of the Classical Pathway Proconvertase

Alessandra Zarantonello, Jessy Présumey, Léa Simoni et al. · The Journal of Immunology · 2020 · 23 citations

Life Sciences, Biochemistry, Immunology +16