Seandean L. Harwood

A tumor-targeted trimeric 4-1BB-agonistic antibody induces potent anti-tumor immunity without systemic toxicity

Marta Compte, Seandean L. Harwood, Inés G. Muñoz et al. · Nature Communications · 2018 · 144 citations · Full text

Life Sciences, Immunology, Oncology +17

ATTACK, a novel bispecific T cell-recruiting antibody with trivalent EGFR binding and monovalent CD3 binding for cancer immunotherapy

Seandean L. Harwood, Ana Álvarez‐Cienfuegos, Natalia Nuñez‐Prado et al. · OncoImmunology · 2017 · 81 citations · Full text

Medicine, Immunology, Oncology +17

Intramolecular trimerization, a novel strategy for making multispecific antibodies with controlled orientation of the antigen binding domains

Ana Álvarez‐Cienfuegos, Natalia Nuñez‐Prado, Marta Compte et al. · Scientific Reports · 2016 · 38 citations · Full text

Pharmacy, Biotechnology, Molecular Biology +17

Structural Investigations of Human A2M Identify a Hollow Native Conformation That Underlies Its Distinctive Protease-Trapping Mechanism

Seandean L. Harwood, Jeppe Lyngsø, Alessandra Zarantonello et al. · Molecular & Cellular Proteomics · 2021 · 37 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Overcoming CAR-Mediated CD19 Downmodulation and Leukemia Relapse with T Lymphocytes Secreting Anti-CD19 T-cell Engagers

Belén Blanco, Ángel Ramírez-Fernández, Clara Bueno et al. · Cancer Immunology Research · 2022 · 32 citations · Full text

Life Sciences, Immunology, Oncology +17