Robert A. Sandhaus

Neutrophil-mediated injury to endothelial cells. Enhancement by endotoxin and essential role of neutrophil elastase.

L A Smedly, Marcia G. Tonnesen, Robert A. Sandhaus et al. · Journal of Clinical Investigation · 1986 · 574 citations · Full text

Veterinary Medicine, Immunology, Pathobiology +17

Intravenous augmentation treatment and lung density in severe α1 antitrypsin deficiency (RAPID): a randomised, double-blind, placebo-controlled trial

Kenneth R. Chapman, Jonathan Burdon, Eeva Piitulainen et al. · The Lancet · 2015 · 504 citations

Medicine, Internal Medicine, Pharmacotherapy +9

Phase 2 Clinical Trial of a Recombinant Adeno-Associated Viral Vector Expressing α ₁ -Antitrypsin: Interim Results

Terence R. Flotte, Bruce C. Trapnell, Margaret Humphries et al. · Human Gene Therapy · 2011 · 327 citations · Full text

Pharmacy, Pharmaceutical Biotechnology, Gene Delivery +12

Experimental emphysema induced with purified human neutrophil elastase: tissue localization of the instilled protease.

Aaron Janoff, Barbara Sloan, George Weinbaum et al. · PubMed · 1977 · 281 citations

Life Sciences, Biochemistry, Immunology +17

A Combined Pulmonary-Radiology Workshop for Visual Evaluation of COPD: Study Design, Chest CT Findings and Concordance with Quantitative Evaluation

Eugene A. Berkowitz, Francesca Bigazzi, F. R. Bode et al. · COPD Journal of Chronic Obstructive Pulmonary Disease · 2012 · 176 citations · Full text

Medicine, Internal Medicine, Radiology +12