Michael Ewing

An Autophagy-Enhancing Drug Promotes Degradation of Mutant α ₁ -Antitrypsin Z and Reduces Hepatic Fibrosis

Tunda Hidvegi, Michael Ewing, Pamela Hale et al. · Science · 2010 · 593 citations

Regulator of G Signaling 16 Is a Marker for the Distinct Endoplasmic Reticulum Stress State Associated with Aggregated Mutant α1-Antitrypsin Z in the Classical Form of α1-Antitrypsin Deficiency

Tunda Hidvegi, Károly Mirnics, Pamela Hale et al. · Journal of Biological Chemistry · 2007 · 82 citations · Full text

ERK and c-Myc signaling in host-derived tumor endothelial cells is essential for solid tumor growth

Zehua Zuo, Jie Liu, Zhihao Sun et al. · Proceedings of the National Academy of Sciences · 2022 · 57 citations · Full text

C-myc Signaling, Immunology, Tumor Endothelial Cells +18

Fluphenazine Reduces Proteotoxicity in C. elegans and Mammalian Models of Alpha-1-Antitrypsin Deficiency

Jie Li, Stephen C. Pak, Linda P. O’Reilly et al. · PLoS ONE · 2014 · 50 citations · Full text

Cell Death, Alpha-1-antitrypsin Deficiency, Toxicological Mechanism +22

Enhancing Autophagy with Drugs or Lung-directed Gene Therapy Reverses the Pathological Effects of Respiratory Epithelial Cell Proteinopathy

Tunda Hidvegi, Donna B. Stolz, John F. Alcorn et al. · Journal of Biological Chemistry · 2015 · 36 citations · Full text

Asthma, Acute Lung Injury, Mitophagy +25