Hikari Osaki

Recurrent mutations, including NPM1c, activate a BRD4-dependent core transcriptional program in acute myeloid leukemia

Mark A. Dawson, Emma Gudgin, Sarah J. Horton et al. · Leukemia · 2013 · 173 citations · Full text

Connectivity mapping identifies HDAC inhibitors for the treatment of t(4;11)-positive infant acute lymphoblastic leukemia

Dominique J. P. M. Stumpel, Pauline Schneider, Lidija Seslija et al. · Leukemia · 2011 · 81 citations

Hematological Malignancy, Oncology, Medicine +9

Early loss of Crebbp confers malignant stem cell properties on lymphoid progenitors

Sarah J. Horton, George Giotopoulos, Haiyang Yun et al. · Nature Cell Biology · 2017 · 67 citations · Full text

Developmental Biology, Tissue Development, Lymphoid Progenitors +7

A novel mouse model identifies cooperating mutations and therapeutic targets critical for chronic myeloid leukemia progression

George Giotopoulos, Louise van der Weyden, Hikari Osaki et al. · The Journal of Experimental Medicine · 2015 · 40 citations · Full text

Hematological Malignancy, Tumor Biology, Chronic Myeloid Leukemia +13

The AAA+ ATPase RUVBL2 is a critical mediator of MLL-AF9 oncogenesis

Hikari Osaki, Vanessa Walf-Vorderwülbecke, Maurizio Mangolini et al. · Leukemia · 2013 · 35 citations

Critical Mediator, Signal Transduction, Molecular Research +10