Single-cell multiomic analysis identifies regulatory programs in mixed-phenotype acute leukemia

Jeffrey M. Granja, Sandy Klemm, Lisa McGinnis, +10

Nature Biotechnology

BioinformaticsFunctional GenomicsSingle Cell SequencingMedicineMixed-phenotype Acute Leukemia +9

Development of a vascular niche platform for expansion of repopulating human cord blood stem and progenitor cells

Jason M. Butler, Eric J. Gars, Daylon James, +3

Blood

Human ESC-derived hemogenic endothelial cells undergo distinct waves of endothelial to hematopoietic transition

Shahin Rafii, Christopher C. Kloss, Jason M. Butler, +13

Blood

Bone marrow histomorphological criteria can accurately diagnose hemophagocytic lymphohistiocytosis

Eric J. Gars, Natasha Purington, Gregory D. Scott, +4

Haematologica

ImmunohematologyLymphocyte DevelopmentImmunodeficienciesImmune RegulationImmunology +23

Activation of the vascular niche supports leukemic progression and resistance to chemotherapy

Michael G. Poulos, Eric J. Gars, Michael Gutkin, +5

Experimental Hematology

Hematological MalignancyMedicineImmunologyOncologyCell Biology +3

Reprogramming Cancer into Antigen-Presenting Cells as a Novel Immunotherapy

Miles H. Linde, Amy C. Fan, Thomas Köhnke, +16

Cancer Discovery

Upregulation of CD47 Is a Host Checkpoint Response to Pathogen Recognition

Michal Caspi Tal, Laughing Bear Torrez Dulgeroff, Lara Myers, +34

mBio

Enasidenib drives human erythroid differentiation independently of isocitrate dehydrogenase 2

Ritika Dutta, Tian Yi Zhang, Thomas Köhnke, +10

Journal of Clinical Investigation

Mixed-phenotype Acute LeukemiaGeneticsImmunologyTransfusion DependenceMyeloid Neoplasia +18

Vulvar Yolk Sac Tumors Are Somatically Derived SMARCB1 (INI-1)-Deficient Neoplasms

David L. Kolin, Panagiotis A. Konstantinopoulos, Susana M. Campos, +4

The American Journal of Surgical Pathology

PathologyCancer BiologyTumor BiologyTesticular TumoursCarcinoma +17

Endothelial cell derived angiocrine support of acute myeloid leukemia targeted by receptor tyrosine kinase inhibition

Leylah Drusbosky, Eric J. Gars, Angelica Trujillo, +5

Leukemia Research