Human ESC-derived hemogenic endothelial cells undergo distinct waves of endothelial to hematopoietic transition - Concepedia

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Human ESC-derived hemogenic endothelial cells undergo distinct waves of endothelial to hematopoietic transition

90

Citations

37

References

2012

Year

Shahin Rafii, Christopher C. Kloss, Jason M. Butler, Michael Ginsberg, Eric J. Gars, Raphaël Lis, Qiansheng Zhan, Pavle Josipović, Bi‐Sen Ding, Jenny Xiang,

Abstract

Live imaging of endothelial to hematopoietic conversion identifies distinct subpopulations of hESC-derived hemogenic endothelium. Expression of the Notch ligand DII4 on vascular ECs drives induction of myeloid fate from hESC-derived hematopoietic progenitors.

References

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