Divergent angiocrine signals from vascular niche balance liver regeneration and fibrosis

Bi‐Sen Ding, Zhongwei Cao, Raphaël Lis, +7

Nature

PathologyCirrhosisAngiogenesisHepatology FibrosisHealth Sciences +14

Targeting of the pulmonary capillary vascular niche promotes lung alveolar repair and ameliorates fibrosis

Zhongwei Cao, Raphaël Lis, Michael Ginsberg, +7

Nature Medicine

Acute Lung InjuryInflammationFibrosisPulmonary CirculationInflammatory Lung Disease +13

Reprogramming human endothelial cells to haematopoietic cells requires vascular induction

Vladislav M. Sandler, Raphaël Lis, Ying Liu, +6

Nature

Endothelial Cell PathobiologyDevelopmental BiologyAngiogenesisVascular AdaptationHematology +7

Conversion of adult endothelium to immunocompetent haematopoietic stem cells

Raphaël Lis, Charles Karrasch, Michael G. Poulos, +15

Nature

Cell TherapyHaematopoietic Stem CellsMedicineStem Cell MobilizationImmunology +6

Pluripotent stem cell-derived epithelium misidentified as brain microvascular endothelium requires ETS factors to acquire vascular fate

Tyler M. Lu, Sean Houghton, Tarig Magdeldin, +13

Proceedings of the National Academy of Sciences

The transcription factor XBP1 is selectively required for eosinophil differentiation

Sarah E. Bettigole, Raphaël Lis, Stanley Adoro, +4

Nature Immunology

Transcriptional RegulationSignal TransductionGeneticsGene RegulationMolecular Genetics +6

Platelet-derived SDF-1 primes the pulmonary capillary vascular niche to drive lung alveolar regeneration

Shahin Rafii, Zhongwei Cao, Raphaël Lis, +5

Nature Cell Biology

Platelet-derived Sdf-1AngiogenesisPulmonary CirculationLung InflammationMedicine +9

Molecular determinants of nephron vascular specialization in the kidney

David M. Barry, Elizabeth A. McMillan, Balvir Kunar, +15

Nature Communications

CCL2/CCL5 secreted by the stroma induce IL-6/PYK2 dependent chemoresistance in ovarian cancer

Jennifer Pasquier, Marie Gosset, Caroline Geyl, +7

Molecular Cancer

Human ESC-derived hemogenic endothelial cells undergo distinct waves of endothelial to hematopoietic transition

Shahin Rafii, Christopher C. Kloss, Jason M. Butler, +13

Blood