T. Haikarainen

Small-Molecule Chemical Probe Rescues Cells from Mono-ADP-Ribosyltransferase ARTD10/PARP10-Induced Apoptosis and Sensitizes Cancer Cells to DNA Damage

Harikanth Venkannagari, Patricia Verheugd, Jarkko Koivunen et al. · Cell chemical biology · 2016 · 71 citations · Full text

Dna Damage, Medicine, Apoptosis +8

Discovery of Tankyrase Inhibiting Flavones with Increased Potency and Isoenzyme Selectivity

Mohit Narwal, Jarkko Koivunen, T. Haikarainen et al. · Journal of Medicinal Chemistry · 2013 · 66 citations · Full text

Bioorganic Chemistry, Pharmaceutical Chemistry, Polyphenolics +19

Structural basis for DNA break recognition by ARTD2/PARP2

Ezeogo Obaji, T. Haikarainen, L. Lehtiö · Nucleic Acids Research · 2018 · 66 citations · Full text

Protein Assembly, Biochemistry, Protein Folding +15

Screening and Structural Analysis of Flavones Inhibiting Tankyrases

Mohit Narwal, T. Haikarainen, Adyary Fallarero et al. · Journal of Medicinal Chemistry · 2013 · 63 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Biochemistry +15

Highly Potent and Isoform Selective Dual Site Binding Tankyrase/Wnt Signaling Inhibitors That Increase Cellular Glucose Uptake and Have Antiproliferative Activity

Amit Nathubhai, T. Haikarainen, Jarkko Koivunen et al. · Journal of Medicinal Chemistry · 2016 · 55 citations · Full text