Sena Garber

Inhibition of Clinically Relevant Mutant Variants of HIV-1 by Quinazolinone Non-Nucleoside Reverse Transcriptase Inhibitors

Jeffrey W. Corbett, Soo S. Ko, James D. Rodgers et al. · Journal of Medicinal Chemistry · 2000 · 299 citations · Full text

Improved cyclic urea inhibitors of the HIV-1 protease: synthesis, potency, resistance profile, human pharmacokinetics and X-ray crystal structure of DMP 450

C. Nicholas Hodge, Paul E. Aldrich, Lee T. Bacheler et al. · Chemistry & Biology · 1996 · 148 citations · Full text

Hiv-1 Protease, Biochemistry, Medicine +9

In vitro isolation and identification of human immunodeficiency virus (HIV) variants with reduced sensitivity to C-2 symmetrical inhibitors of HIV type 1 protease.

M. J. Otto, Sena Garber, Dean L. Winslow et al. · Proceedings of the National Academy of Sciences · 1993 · 129 citations · Full text

Immunology, Molecular Biology, Vitro Isolation +19

Cyclic Urea Amides:  HIV-1 Protease Inhibitors with Low Nanomolar Potency against both Wild Type and Protease Inhibitor Resistant Mutants of HIV

Prabhakar K. Jadhav, Paul Ala, Francis J. Woerner et al. · Journal of Medicinal Chemistry · 1997 · 113 citations · Full text

Low Nanomolar Potency, Molecular Biology, Antiviral Drug +19

Drug design with a new transition state analog of the hydrated carbonyl: silicon-based inhibitors of the HIV protease

Chien-An Chen, Scott McN. Sieburth, Athanasios Glekas et al. · Chemistry & Biology · 2001 · 85 citations · Full text

Medicinal Chemistry, Hiv Protease, Drug Design +11