Clare S. W. Yan

Amine Linked Flavonoid Dimers as Modulators for P-Glycoprotein-Based Multidrug Resistance: Structure–Activity Relationship and Mechanism of Modulation

Kin‐Fai Chan, Iris L. K. Wong, Jason W. Y. Kan et al. · Journal of Medicinal Chemistry · 2012 · 69 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Design and Syntheses of Permethyl Ningalin B Analogues: Potent Multidrug Resistance (MDR) Reversal Agents of Cancer Cells

Pu Yong Zhang, Iris L. K. Wong, Clare S. W. Yan et al. · Journal of Medicinal Chemistry · 2010 · 60 citations

Medicine, Medicinal Chemistry, Pharmacology +14

Flavonoid Dimers as Bivalent Modulators for P‐Glycoprotein‐Based Multidrug Resistance: Structure–Activity Relationships

Kin‐Fai Chan, Yunzhe Zhao, Toby W. S. Chow et al. · ChemMedChem · 2009 · 49 citations

Medicine, Medicinal Chemistry, Pharmacology +14

A New Class of Safe, Potent, and Specific P-gp Modulator: Flavonoid Dimer <b>FD18</b> Reverses P-gp-Mediated Multidrug Resistance in Human Breast Xenograft <i>in Vivo</i>

Clare S. W. Yan, Iris L. K. Wong, Kin‐Fai Chan et al. · Molecular Pharmaceutics · 2015 · 20 citations

Medicine, Oncology, Pharmacology +16

Discovery of a Flavonoid FM04 as a Potent Inhibitor to Reverse P-Glycoprotein-Mediated Drug Resistance in Xenografts and Improve Oral Bioavailability of Paclitaxel

Jason W. Y. Kan, Clare S. W. Yan, Iris L. K. Wong et al. · International Journal of Molecular Sciences · 2022 · 12 citations · Full text

Medicine, Oncology, Pharmacology +17