Jason W. Y. Kan

Amine Linked Flavonoid Dimers as Modulators for P-Glycoprotein-Based Multidrug Resistance: Structure–Activity Relationship and Mechanism of Modulation

Kin‐Fai Chan, Iris L. K. Wong, Jason W. Y. Kan et al. · Journal of Medicinal Chemistry · 2012 · 69 citations · Full text

Structure–activity Relationship, Pharmaceutical Science, Reversal Potency +22

Boosting the efficacy of anti-MRSA β-lactam antibiotics via an easily accessible, non-cytotoxic and orally bioavailable FtsZ inhibitor

Hok Kiu Lui, Wei Gao, Kwan Choi Cheung et al. · European Journal of Medicinal Chemistry · 2018 · 33 citations · Full text

Anti-mrsa β-Lactam Antibiotics, Antimicrobial Drug Discovery, Antimicrobial Stewardship +14

A New Class of Safe, Potent, and Specific P-gp Modulator: Flavonoid Dimer <b>FD18</b> Reverses P-gp-Mediated Multidrug Resistance in Human Breast Xenograft <i>in Vivo</i>

Clare S. W. Yan, Iris L. K. Wong, Kin‐Fai Chan et al. · Molecular Pharmaceutics · 2015 · 19 citations

Discovery of a Flavonoid FM04 as a Potent Inhibitor to Reverse P-Glycoprotein-Mediated Drug Resistance in Xenografts and Improve Oral Bioavailability of Paclitaxel

Jason W. Y. Kan, Clare S. W. Yan, Iris L. K. Wong et al. · International Journal of Molecular Sciences · 2022 · 12 citations · Full text

Pharmaceutical Science, Pharmacotherapy, Pharmaceutical Chemistry +20