Iris L. K. Wong

A Global Trend Analysis of Kidney Cancer Incidence and Mortality and Their Associations with Smoking, Alcohol Consumption, and Metabolic Syndrome

Junjie Huang, David Leung, Erica On-Ting Chan et al. · European Urology Focus · 2021 · 117 citations

Medicine, Nephrology, Oncology +16

Flavonoid Dimers as Bivalent Modulators for P-Glycoprotein-Based Multidrug Resistance:  Synthetic Apigenin Homodimers Linked with Defined-Length Poly(ethylene glycol) Spacers Increase Drug Retention and Enhance Chemosensitivity in Resistant Cancer Cells

Kin‐Fai Chan, Yunzhe Zhao, Brendan A. Burkett et al. · Journal of Medicinal Chemistry · 2006 · 95 citations

Medicine, Medicinal Chemistry, Pharmacology +15

Modulation of Multidrug Resistance Protein 1 (MRP1/ABCC1)-Mediated Multidrug Resistance by Bivalent Apigenin Homodimers and Their Derivatives

Iris L. K. Wong, Kin‐Fai Chan, Ka Hing Tsang et al. · Journal of Medicinal Chemistry · 2009 · 87 citations · Full text

Medicine, Oncology, Pharmacology +17

Amine Linked Flavonoid Dimers as Modulators for P-Glycoprotein-Based Multidrug Resistance: Structure–Activity Relationship and Mechanism of Modulation

Kin‐Fai Chan, Iris L. K. Wong, Jason W. Y. Kan et al. · Journal of Medicinal Chemistry · 2012 · 69 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Synthesis of methylated quercetin derivatives and their reversal activities on P-gp- and BCRP-mediated multidrug resistance tumour cells

Jian‐Min Yuan, Iris L. K. Wong, Tao Jiang et al. · European Journal of Medicinal Chemistry · 2012 · 63 citations

Medicine, Medicinal Chemistry, Pharmacology +15