Takashi Matsuwaki

Alteration of behavioural phenotype in mice by targeted disruption of the progranulin gene

Yuko Kayasuga, Shuichi Chiba, Masatoshi Suzuki et al. · Behavioural Brain Research · 2007 · 190 citations

Knockout Mouse, Developmental Biology, Molecular Neuroscience +7

Progranulin regulates lysosomal function and biogenesis through acidification of lysosomes

Yoshinori Tanaka, Genjiro Suzuki, Takashi Matsuwaki et al. · Human Molecular Genetics · 2017 · 176 citations

Protein Function, Developmental Biology, Molecular Neuroscience +14

Granulin Is a Soluble Cofactor for Toll-like Receptor 9 Signaling

Boyoun Park, Ludovico Buti, Sungwook Lee et al. · Immunity · 2011 · 172 citations · Full text

Inflammation, Toll-like Receptors, Molecular Immunology +12

Proteolytic processing of TAR DNA binding protein‐43 by caspases produces C‐terminal fragments with disease defining properties independent of progranulin

Dorothee Dormann, Anja Capell, Aaron Carlson et al. · Journal of Neurochemistry · 2009 · 159 citations

Possible involvement of lysosomal dysfunction in pathological changes of the brain in aged progranulin-deficient mice

Yoshinori Tanaka, James Chambers, Takashi Matsuwaki et al. · Acta Neuropathologica Communications · 2014 · 156 citations · Full text