Emily R. Theisen

High-Throughput Virtual Screening Identifies Novel <i>N</i>′-(1-Phenylethylidene)-benzohydrazides as Potent, Specific, and Reversible LSD1 Inhibitors

Venkataswamy Sorna, Emily R. Theisen, Bret J. Stephens et al. · Journal of Medicinal Chemistry · 2013 · 206 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Reversible LSD1 Inhibition Interferes with Global EWS/ETS Transcriptional Activity and Impedes Ewing Sarcoma Tumor Growth

Savita Sankar, Emily R. Theisen, Jared Bearss et al. · Clinical Cancer Research · 2014 · 182 citations · Full text

Medicine, Cancer Biology, Oncology +14

Role for the EWS domain of EWS/FLI in binding GGAA-microsatellites required for Ewing sarcoma anchorage independent growth

Kirsten M. Johnson, Nathan Mahler, Ranajeet S. Saund et al. · Proceedings of the National Academy of Sciences · 2017 · 87 citations · Full text

Medicine, Molecular Biology, Oncology +17

Therapeutic Targeting of KDM1A/LSD1 in Ewing Sarcoma with SP-2509 Engages the Endoplasmic Reticulum Stress Response

Kathleen I. Pishas, Christina D. Drenberg, Cenny Taslim et al. · Molecular Cancer Therapeutics · 2018 · 67 citations

Medicine, Oncology, Pharmacology +13

EWS/FLI mediated reprogramming of 3D chromatin promotes an altered transcriptional state in Ewing sarcoma

Iftekhar A. Showpnil, Julia Selich‐Anderson, Cenny Taslim et al. · Nucleic Acids Research · 2022 · 51 citations · Full text

Life Sciences, Cancer Biology, Genetics +17