Venkataswamy Sorna

High-Throughput Virtual Screening Identifies Novel <i>N</i>′-(1-Phenylethylidene)-benzohydrazides as Potent, Specific, and Reversible LSD1 Inhibitors

Venkataswamy Sorna, Emily R. Theisen, Bret J. Stephens et al. · Journal of Medicinal Chemistry · 2013 · 205 citations · Full text

Drug Target, Hit Identification, Histone Lysine Methylation +21

Reversible LSD1 Inhibition Interferes with Global EWS/ETS Transcriptional Activity and Impedes Ewing Sarcoma Tumor Growth

Savita Sankar, Emily R. Theisen, Jared Bearss et al. · Clinical Cancer Research · 2014 · 176 citations · Full text

Reversible inhibition of lysine specific demethylase 1 is a novel anti-tumor strategy for poorly differentiated endometrial carcinoma

Emily R. Theisen, Snehal Gajiwala, Jared Bearss et al. · BMC Cancer · 2014 · 48 citations · Full text

Design, Synthesis, and Biological Evaluation of a Series of Anthracene-9,10-dione Dioxime β-Catenin Pathway Inhibitors

Raffaella Soldi, Stephen Horrigan, Marek Chołody et al. · Journal of Medicinal Chemistry · 2015 · 27 citations · Full text

Chemoprevention Strategy, Chemical Biology, Pharmaceutical Chemistry +19

Fragment-based design, synthesis, biological evaluation, and SAR of 1H-benzo[d]imidazol-2-yl)-1H-indazol derivatives as potent PDK1 inhibitors

Ting Chen, Venkataswamy Sorna, Susie Choi et al. · Bioorganic & Medicinal Chemistry Letters · 2017 · 14 citations · Full text