USP21 negatively regulates antiviral response by acting as a RIG-I deubiquitinase

Yihui Fan, Renfang Mao, Yu Yang, +16

The Journal of Experimental Medicine

Rna Virus InfectionRig-i DeubiquitinaseImmunologyViral PathogenesisImmune Regulation +17

Lysine 63-linked Polyubiquitination of TAK1 at Lysine 158 Is Required for Tumor Necrosis Factor α- and Interleukin-1β-induced IKK/NF-κB and JNK/AP-1 Activation

Yihui Fan, Yang Yu, Yi Shi, +11

Journal of Biological Chemistry

ImmunologyImmune RegulationCell DeathTak1 PolyubiquitinationImmunologic Mechanism +22

Pan-Cancer Analysis Reveals Disrupted Circadian Clock Associates With T Cell Exhaustion

Yingcheng Wu, Baorui Tao, Tianyang Zhang, +2

Frontiers in Immunology

USP11 negatively regulates TNFα-induced NF-κB activation by targeting on IκBα

Wenjing Sun, Xiaojie Tan, Yi Shi, +14

Cellular Signalling

InflammationCytokineTranscriptional RegulationSignal TransductionSignaling Pathway +10

TAK1 lysine 158 is required for TGF-β-induced TRAF6-mediated Smad-independent IKK/NF-κB and JNK/AP-1 activation

Renfang Mao, Yihui Fan, Yonggao Mou, +3

Cellular Signalling

Transcriptional RegulationJnk/ap-1 ActivationSignal TransductionMolecular PhysiologySignaling Pathway +7

AIBP Limits Angiogenesis Through γ-Secretase-Mediated Upregulation of Notch Signaling

Renfang Mao, Shu Meng, Qilin Gu, +10

Circulation Research

A Tumor-Specific Super-Enhancer Drives Immune Evasion by Guiding Synchronous Expression of PD-L1 and PD-L2

Yuanpei Xu, Yingcheng Wu, Siliang Zhang, +14

Cell Reports

Frequency of double minute chromosomes and combined cytogenetic abnormalities and their characteristics

Yihui Fan, Renfang Mao, Hongpei Lv, +9

Journal of Applied Genetics

ChromatinGenome InstabilityDevelopmental BiologyCytogeneticsGenetic Disorder +8

TAK1 Lys-158 but not Lys-209 is required for IL-1β-induced Lys63-linked TAK1 polyubiquitination and IKK/NF-κB activation

Yihui Fan, Yang Yu, Renfang Mao, +2

Cellular Signalling

InflammationCytokineTranscriptional RegulationTak1 Lys-158Immune Cell Development +11

HPV shapes tumor transcriptome by globally modifying the pool of RNA binding protein-binding motif

Yingcheng Wu, Hao Chen, Yuyan Chen, +8

Aging

Molecular BiologyPositive HeadHpv InfectionCancer-associated VirusTranscriptional Regulation +14