Binje Vick

Small-molecule inhibition of METTL3 as a strategy against myeloid leukaemia

Eliza Yankova, Wesley Blackaby, Mark R. Albertella et al. · Nature · 2021 · 1.2K citations · Full text

Hematological Malignancy, Tumor Biology, Medicine +9

The target landscape of clinical kinase drugs

Susan Klaeger, Stephanie Heinzlmeir, Mathias Wilhelm et al. · Science · 2017 · 845 citations · Full text

Tumor Biology, Proteomicsdb Database, Drug Target +14

Loss of the histone methyltransferase EZH2 induces resistance to multiple drugs in acute myeloid leukemia

Stefanie Göllner, Thomas Oellerich, Shuchi Agrawal‐Singh et al. · Nature Medicine · 2016 · 252 citations · Full text

Histone Modifications, Chromatin, Hematological Malignancy +11

Blockade of the PD-1/PD-L1 axis augments lysis of AML cells by the CD33/CD3 BiTE antibody construct AMG 330: reversing a T-cell-induced immune escape mechanism

Christina Krupka, Peter Kufer, Roman Kischel et al. · Leukemia · 2015 · 239 citations

Autoimmune Disease, Immunology, Immunologic Mechanism +8

T-cell exhaustion induced by continuous bispecific molecule exposure is ameliorated by treatment-free intervals

Nora Philipp, Maryam Kazerani, Alyssa Nicholls et al. · Blood · 2022 · 215 citations · Full text

T-regulatory Cell, Immunology, Immunologic Mechanism +23