Binje Vick

Small-molecule inhibition of METTL3 as a strategy against myeloid leukaemia

Eliza Yankova, Wesley Blackaby, Mark R. Albertella et al. · Nature · 2021 · 1.3K citations · Full text

Medicine, Oncology, Pharmacology +13

The target landscape of clinical kinase drugs

Susan Klaeger, Stephanie Heinzlmeir, Mathias Wilhelm et al. · Science · 2017 · 871 citations · Full text

Medicine, Oncology, Pharmacology +15

Loss of the histone methyltransferase EZH2 induces resistance to multiple drugs in acute myeloid leukemia

Stefanie Göllner, Thomas Oellerich, Shuchi Agrawal‐Singh et al. · Nature Medicine · 2016 · 267 citations · Full text

Life Sciences, Molecular Biology, Oncology +14

Blockade of the PD-1/PD-L1 axis augments lysis of AML cells by the CD33/CD3 BiTE antibody construct AMG 330: reversing a T-cell-induced immune escape mechanism

Christina Krupka, Peter Kufer, Roman Kischel et al. · Leukemia · 2015 · 249 citations

Life Sciences, Immunology, Oncology +16

T-cell exhaustion induced by continuous bispecific molecule exposure is ameliorated by treatment-free intervals

Nora Philipp, Maryam Kazerani, Alyssa Nicholls et al. · Blood · 2022 · 245 citations · Full text

Life Sciences, Immunology, Oncology +17