Yannick P. Kok

Elongation factor ELOF1 drives transcription-coupled repair and prevents genome instability

Marit E. Geijer, Di Zhou, Kathiresan Selvam et al. · Nature Cell Biology · 2021 · 95 citations · Full text

Genome Instability, Transcriptional Regulation, Chromatin Remodeling +7

Overexpression of Cyclin E1 or Cdc25A leads to replication stress, mitotic aberrancies, and increased sensitivity to replication checkpoint inhibitors

Yannick P. Kok, Sergi Guerrero Llobet, Pepijn M. Schoonen et al. · Oncogenesis · 2020 · 92 citations · Full text

Premature mitotic entry induced by ATR inhibition potentiates olaparib inhibition‐mediated genomic instability, inflammatory signaling, and cytotoxicity in BRCA2‐deficient cancer cells

Pepijn M. Schoonen, Yannick P. Kok, Elles Wierenga et al. · Molecular Oncology · 2019 · 82 citations · Full text

Cell Death, Cancer Biology, Tumor Biology +17

TPX2/Aurora kinase A signaling as a potential therapeutic target in genomically unstable cancer cells

Stephanie E. van Gijn, Elles Wierenga, Nathalie van den Tempel et al. · Oncogene · 2018 · 67 citations · Full text

Modeling of Cisplatin-Induced Signaling Dynamics in Triple-Negative Breast Cancer Cells Reveals Mediators of Sensitivity

Anne Margriet Heijink, Marieke Everts, Megan E. Honeywell et al. · Cell Reports · 2019 · 41 citations · Full text