J. J. Roberts

Mechanism of cytotoxicity of anticancer platinum drugs: evidence that cis-diamminedichloroplatinum(II) and cis-diammine-(1,1-cyclobutanedicarboxylato)platinum(II) differ only in the kinetics of their interaction with DNA.

Richard J. Knox, Frank Friedlos, David Lydall et al. · PubMed · 1986 · 499 citations

Chemoprevention Strategy, Chemical Biology, Toxicological Mechanism +19

The Mechanism of Action of Antitumor Platinum Compounds

J. J. Roberts, Andrew J. Thomson · Progress in nucleic acid research and molecular biology · 1979 · 410 citations

Medicinal Chemistry, Medicine, Antitumor Platinum Compounds +4

Epidemic of AIDS related virus (HTLV-III/LAV) infection among intravenous drug abusers.

J R Robertson, A B Bucknall, P D Welsby et al. · BMJ · 1986 · 309 citations · Full text

Cross-linking of Complementary Strands of DNA in Mammalian Cells by Antitumour Platinum Compounds

J. J. Roberts, Janet M. Pascoe · Nature · 1972 · 246 citations

Chromatin, Cross-link, Medicine +11

Interactions between mammalian cell DNA and inorganic platinum compounds—I

Janet M. Pascoe, J. J. Roberts · Biochemical Pharmacology · 1974 · 237 citations

Mammalian Cell Dna, Nucleic Acid Chemistry, Natural Sciences +2