Martje Tönjes

Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma

Jeremy Schwartzentruber, Andrey Korshunov, Xiao-Yang Liu et al. · Nature · 2012 · 2.6K citations

Chromatin, Neuro-oncology, Chromatin Structure +13

Hotspot Mutations in H3F3A and IDH1 Define Distinct Epigenetic and Biological Subgroups of Glioblastoma

Dominik Sturm, Hendrik Witt, Volker Hovestadt et al. · Cancer Cell · 2012 · 1.8K citations · Full text

Neuro-oncology, Radiation Oncology, Somatic Variant +11

BCAT1 promotes cell proliferation through amino acid catabolism in gliomas carrying wild-type IDH1

Martje Tönjes, Sebastian Barbus, Yoon Jung Park et al. · Nature Medicine · 2013 · 463 citations

Neuro-oncology, Medicine, Wild-type Idh1 +11

Frequent ATRX mutations and loss of expression in adult diffuse astrocytic tumors carrying IDH1/IDH2 and TP53 mutations

Xiaoyang Liu, Noha Gerges, Andrey Korshunov et al. · Acta Neuropathologica · 2012 · 411 citations

Somatic Variant, Glioma, Pathology +7

BCAT1 restricts αKG levels in AML stem cells leading to IDHmut-like DNA hypermethylation

Simon Raffel, Mattia Falcone, Niclas Kneisel et al. · Nature · 2017 · 341 citations

Idhmut-like Dna Hypermethylation, Chromatin, Transcriptional Regulation +14