J R Taylor

Synthetic lethal targeting of <i>PTEN</i> mutant cells with PARP inhibitors

Ana M. Mendes‐Pereira, Sarah A. Martin, Rachel Brough et al. · EMBO Molecular Medicine · 2009 · 618 citations · Full text

Drug Targeting, Synthetic Lethal Targeting, Molecular Biology +7

Suppression of PTEN function increases breast cancer chemotherapeutic drug resistance while conferring sensitivity to mTOR inhibitors

Linda S. Steelman, Patrick M. Navolanic, Melissa L. Sokolosky et al. · Oncogene · 2008 · 171 citations · Full text

Breast Oncology, Pten Function Increases, Medicine +7

FMS receptor for M-CSF (CSF-1) is sensitive to the kinase inhibitor imatinib and mutation of Asp-802 to Val confers resistance

J R Taylor, Nicola Brownlow, J. Domin et al. · Oncogene · 2005 · 58 citations

Kinase Inhibitor Imatinib, Signal Transduction, Signaling Pathway +7

Harnessing the tumour-derived cytokine, CSF-1, to co-stimulate T-cell growth and activation

Agnes Shuk Yee Lo, J R Taylor, Farzin Farzaneh et al. · Molecular Immunology · 2007 · 44 citations

Cytokine, Cancer Immunosurveillance, Tumour-derived Cytokine +9