Karen O’Dwyer

Identification and manipulation of the pleuromutilin gene cluster from Clitopilus passeckerianus for increased rapid antibiotic production

Andy M. Bailey, Fabrizio Alberti, Sreedhar Kilaru et al. · Scientific Reports · 2016 · 116 citations · Full text

Life Sciences, Biotechnology, Microbiology +15

Bacterial Resistance to Leucyl-tRNA Synthetase Inhibitor GSK2251052 Develops during Treatment of Complicated Urinary Tract Infections

Karen O’Dwyer, Aaron Spivak, Karen Ingraham et al. · Antimicrobial Agents and Chemotherapy · 2014 · 98 citations · Full text

Life Sciences, Infectious Diseases, Microbiology +17

Characterization of a Novel Fucose-Regulated Promoter (P_<i>fcsK</i>) Suitable for Gene Essentiality and Antibacterial Mode-of-Action Studies in<i>Streptococcus pneumoniae</i>

Pan F. Chan, Karen O’Dwyer, Leslie M. Palmer et al. · Journal of Bacteriology · 2003 · 90 citations · Full text

Life Sciences, Microbiology, Molecular Biology +15

A Global Approach to Identify Novel Broad-Spectrum Antibacterial Targets among Proteins of Unknown Function

Magdalena Zalacaín, Sanjoy Kanti Biswas, Karen Ingraham et al. · Microbial Physiology · 2003 · 86 citations

Life Sciences, Genetics, Microbiology +9

Lipopeptide substrates for SpsB, the Staphylococcus aureus type I signal peptidase: design, conformation and conversion to α-ketoamide inhibitors

Gordon Bruton, Anthony Huxley, Peter J. O’Hanlon et al. · European Journal of Medicinal Chemistry · 2003 · 52 citations

Life Sciences, Biochemistry, Molecular Biology +11