Karen O’Dwyer

Identification and manipulation of the pleuromutilin gene cluster from Clitopilus passeckerianus for increased rapid antibiotic production

Andy M. Bailey, Fabrizio Alberti, Sreedhar Kilaru et al. · Scientific Reports · 2016 · 114 citations · Full text

Bacterial Resistance to Leucyl-tRNA Synthetase Inhibitor GSK2251052 Develops during Treatment of Complicated Urinary Tract Infections

Karen O’Dwyer, Aaron Spivak, Karen Ingraham et al. · Antimicrobial Agents and Chemotherapy · 2014 · 97 citations · Full text

Microbial Pathogens, Escherichia Coli Isolates, Antibiotic Resistance +21

Characterization of a Novel Fucose-Regulated Promoter (P_<i>fcsK</i>) Suitable for Gene Essentiality and Antibacterial Mode-of-Action Studies in<i>Streptococcus pneumoniae</i>

Pan F. Chan, Karen O’Dwyer, Leslie M. Palmer et al. · Journal of Bacteriology · 2003 · 90 citations · Full text

Microbial Pathogens, Klebsiella Pneumoniae, Bacteriology +21

A Global Approach to Identify Novel Broad-Spectrum Antibacterial Targets among Proteins of Unknown Function

Magdalena Zalacaín, Sanjoy Kanti Biswas, Karen Ingraham et al. · Microbial Physiology · 2003 · 86 citations

Lipopeptide substrates for SpsB, the Staphylococcus aureus type I signal peptidase: design, conformation and conversion to α-ketoamide inhibitors

Gordon Bruton, Anthony Huxley, Peter J. O’Hanlon et al. · European Journal of Medicinal Chemistry · 2003 · 52 citations

α-Ketoamide Inhibitors, Signal Peptidase, Antimicrobial Drug Discovery +10