Marta Nevalainen

Total Synthesis of Thiostrepton. Retrosynthetic Analysis and Construction of Key Building Blocks

K. C. Nicolaou, Brian S. Safina, Mark Zak et al. · Journal of the American Chemical Society · 2005 · 132 citations

Natural Sciences, Chemistry, Medicinal Chemistry +12

Semisynthetic Cyclopamine Analogues as Potent and Orally Bioavailable Hedgehog Pathway Antagonists

Martin Tremblay, Marta Nevalainen, Somarajan Nair et al. · Journal of Medicinal Chemistry · 2008 · 107 citations

Pharmacy, Medicinal Chemistry, Pharmacology +13

Total Synthesis of Thiostrepton. Assembly of Key Building Blocks and Completion of the Synthesis

K. C. Nicolaou, Mark Zak, Brian S. Safina et al. · Journal of the American Chemical Society · 2005 · 95 citations

Pharmacy, Chemistry, Medicinal Chemistry +14

A new organocatalyst for 1,3-dipolar cycloadditions of nitrones to α,β-unsaturated aldehydes

San San Chow, Marta Nevalainen, Catherine A. Evans et al. · Tetrahedron Letters · 2006 · 90 citations

Natural Sciences, Chemistry, Medicinal Chemistry +7

A Biomimetically Inspired Synthesis of the Dehydropiperidine Domain of Thiostrepton We thank Drs. D. H. Huang and L. Pasternack, G. Suizdak, and R. Chadja for NMR spectroscopic, mass spectrometric, and X-ray crystallographic assistance, respectively. Financial support for this work was provided by The Skaggs Institute for Chemical Biology, the National Institutes of Health (USA), fellowships from The Academy of Finland (M.N.), The Skaggs Institute for Research (M.Z.), and Bayer AG (S.B.), and grants from Abbott, Amgen, Array Biopharma, Boehringer-Ingelheim, Glaxo, Hoffmann-LaRoche, DuPont, Merck, Novartis, Pfizer, and Schering Plough.

K. C. Nicolaou, Marta Nevalainen, Brian S. Safina et al. · Angewandte Chemie International Edition · 2002 · 72 citations

Natural Sciences, Biochemistry, Chemistry +5