Catherine F. Clarke

Target identification using drug affinity responsive target stability (DARTS)

Brett Lomenick, Rui Hao, Nao Jonai et al. · Proceedings of the National Academy of Sciences · 2009 · 1.1K citations · Full text

Pharmacy, Pharmaceutics, Pharmacology +13

The metabolite α-ketoglutarate extends lifespan by inhibiting ATP synthase and TOR

R Chin, Xudong Fu, Melody Y. Pai et al. · Nature · 2014 · 612 citations · Full text

Life Sciences, Biochemistry, Physiology +14

COQ6 mutations in human patients produce nephrotic syndrome with sensorineural deafness

Saskia F. Heeringa, Gil Chernin, Moumita Chaki et al. · Journal of Clinical Investigation · 2011 · 400 citations · Full text

Medicine, Genetics, Molecular Genetics +17

ADCK4 mutations promote steroid-resistant nephrotic syndrome through CoQ10 biosynthesis disruption

Shazia Ashraf, Heon Yung Gee, Stéphanie Woerner et al. · Journal of Clinical Investigation · 2013 · 341 citations · Full text

Medicine, Genetics, Molecular Genetics +15

Extension of Life-Span in <i>Caenorhabditis elegans</i> by a Diet Lacking Coenzyme Q

Pamela L. Larsen, Catherine F. Clarke · Science · 2002 · 250 citations

Life Sciences, Biochemistry, Biology +17