LSH mediates gene repression through macroH2A deposition

Kai Ni, Jianke Ren, Xiaoping Xu, +6

Nature Communications

Macrolactin S, a novel macrolactin antibiotic from marine<b><i>Bacillus</i></b>sp.

Xiaoling Lu, Qiu-Hua Xu, Yang Shen, +4

Natural Product Research

Antimicrobial Drug DiscoveryMarine BiotechnologyAntimicrobial SusceptibilityMacrolactin BBacteriology +8

LSH catalyzes ATP-driven exchange of histone variants macroH2A1 and macroH2A2

Kai Ni, Kathrin Muegge

Nucleic Acids Research

The epigenetic regulator LSH maintains fork protection and genomic stability via MacroH2A deposition and RAD51 filament formation

Xiaoping Xu, Kai Ni, Yafeng He, +9

Nature Communications

Alopecurone B reverses doxorubicin-resistant human osteosarcoma cell line by inhibiting P-glycoprotein and NF-kappa B signaling

Yuan‐Zheng Xia, Kai Ni, Chao Guo, +5

Phytomedicine

Oncogenic AgentMedicineImmunologyNf-kappa BPathology +6

Naringin as a plant-derived bitter tastant promotes proliferation of cultured human airway epithelial cells via activation of TAS2R signaling

Kai Ni, Jia Guo, Bing Bu, +5

Phytomedicine

AsthmaPhytoalexinSignal TransductionLung InflammationMedicine +8

The chromatin remodeling protein Lsh alters nucleosome occupancy at putative enhancers and modulates binding of lineage specific transcription factors

Jianke Ren, Richard Finney, Kai Ni, +2

Epigenetics

Histone ModificationsEpigenetic ChangeGeneticsPutative EnhancersProtein Lsh +20

Lsh/HELLS is required for B lymphocyte development and immunoglobulin class switch recombination

Yafeng He, Jianke Ren, Xiaoping Xu, +10

Proceedings of the National Academy of Sciences

Toward the Identification of Extra-Oral TAS2R Agonists as Drug Agents for Muscle Relaxation Therapies via Bioinformatics-Aided Screening of Bitter Compounds in Traditional Chinese Medicine

Mingzhi Luo, Kai Ni, Yang Jin, +2

Frontiers in Physiology

Medicinal ChemistryMuscle FunctionPharmacological StudyTraditional Chinese MedicineMedicine +13

Flavonostilbenes from <i>Sophora alopecuroides</i> L. as multidrug resistance associated protein 1 (MRP1) inhibitors

Kai Ni, Lei Yang, Chuanxing Wan, +2

Natural Product Research