Concepedia
Statistics
Publications
13
Citations
464
H-Index
10
Active since
2015
Affiliations
University of Oxford(Current)
Stanford University
Science Oxford
Radboud University Nijmegen
University of Bristol
Robert K. Leśniak is an author at University of Oxford specializing in natural sciences, chemical biology, and drug discovery.
Top concepts
Natural SciencesMedicineBiochemistryDrug DiscoveryChemical BiologyMolecular BiologyBiocatalysisPharmacologyProtein AssemblyAntimicrobial Drug Discovery
Publications per year
2015–2022
Discovery and Characterization of GSK2801, a Selective Chemical Probe for the Bromodomains BAZ2A and BAZ2B
Peiling Chen, A. Chaikuad, Paul Bamborough et al. · Journal of Medicinal Chemistry · 2015 · 160 citations · Full text
Baz2 Bromodomains, Protein Assembly, Molecular Biology +16
Imitation of β-lactam binding enables broad-spectrum metallo-β-lactamase inhibitors
Jürgen Brem, Tharindi Panduwawala, Jon Hansen et al. · Nature Chemistry · 2021 · 77 citations · Full text
Molecular Pharmacology, Medicinal Chemistry, Antimicrobial Drug Discovery +11
The Jumonji-C oxygenase JMJD7 catalyzes (3S)-lysyl hydroxylation of TRAFAC GTPases
Suzana Markolovic, Qinqin Zhuang, Sarah E. Wilkins et al. · Nature Chemical Biology · 2018 · 43 citations · Full text
Biosynthesis, Bioorganic Chemistry, Cellular Enzymology +9
High-Throughput Crystallography Reveals Boron-Containing Inhibitors of a Penicillin-Binding Protein with Di- and Tricovalent Binding Modes
Hector Newman, Alen Krajnc, Dom Bellini et al. · Journal of Medicinal Chemistry · 2021 · 32 citations · Full text
Crystallographic analyses of isoquinoline complexes reveal a new mode of metallo-β-lactamase inhibition
Guo‐Bo Li, Jürgen Brem, Robert K. Leśniak et al. · Chemical Communications · 2017 · 29 citations · Full text
Inhibitory Activity, Antimicrobial Drug Discovery, Biochemistry +14
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