Kinetic properties of the glucose‐6‐phosphate and 6 phosphogluconate dehydrogenases from <i>Corynebacterium glutamicum</i> and their application for predicting pentose phosphate pathway flux <i>in vivo</i>

Bernd Moritz, Katharina Striegel, Albert A. de Graaf, +1

European Journal of Biochemistry

Simultaneous Assessment of Asp Isomerization and Asn Deamidation in Recombinant Antibodies by LC-MS following Incubation at Elevated Temperatures

Katharina Diepold, Katrin Bomans, Michael Wiedmann, +9

PLoS ONE

ImmunologyImmunodominanceMolecular BiologyProtein PurificationProtein Folding +21

Evaluation of capillary zone electrophoresis for charge heterogeneity testing of monoclonal antibodies

Bernd Moritz, Volker Schnaible, Steffen Kiessig, +17

Journal of Chromatography B

Charge Heterogeneity TestingCapillary ElectrophoresisMedicineBioanalysisAntibody Screening +11

Two-dimensional capillary zone electrophoresis–mass spectrometry for the characterization of intact monoclonal antibody charge variants, including deamidation products

Kevin Jooß, Jens Hühner, Steffen Kiessig, +2

Analytical and Bioanalytical Chemistry

Capillary ElectrophoresisBiochemistryNatural SciencesDeamidation ProductsBioanalysis +11

Changes of Pentose Phosphate Pathway Flux in Vivo in Corynebacterium glutamicum during Leucine-Limited Batch Cultivation as Determined from Intracellular Metabolite Concentration Measurements

Bernd Moritz, Katharina Striegel, Albert A. de Graaf, +1

Metabolic Engineering

Corynebacterium GlutamicumBiosynthesisEngineeringBiochemistryIn Vitro Fermentation +8

Optimization of capillary zone electrophoresis for charge heterogeneity testing of biopharmaceuticals using enhanced method development principles

Bernd Moritz, Valentina Locatelli, Michele Niess, +6

Electrophoresis

Capillary Zone ElectrophoresisProtein PurificationSeparation ScienceBioanalysisAnalytical Chemistry +18

Characterization of therapeutic mAb charge heterogeneity by iCIEF coupled to mass spectrometry (iCIEF–MS)

Johannes Schlecht, Bernd Moritz, Steffen Kiessig, +1

Electrophoresis

Immunocytochemical TechniqueEngineeringTherapeutic MabImmunologyBiological Mass Spectrometry +18

Online mass spectrometry of CE (SDS)-separated proteins by two-dimensional capillary electrophoresis

Jennifer Römer, Cristina Montealegre, Johannes Schlecht, +3

Analytical and Bioanalytical Chemistry

EngineeringCapillary ElectrophoresisBiochemistryMedicineBioanalysis +9

In‐capillary approach to eliminate SDS interferences in antibody analysis by capillary electrophoresis coupled to mass spectrometry

Laura Sánchez‐Hernández, Cristina Montealegre, Steffen Kiessig, +2

Electrophoresis

Online top-down mass spectrometric identification of CE(SDS)-separated antibody fragments by two-dimensional capillary electrophoresis

Jennifer Römer, A. Stolz, Steffen Kiessig, +2

Journal of Pharmaceutical and Biomedical Analysis