IL-4/IL-13 pathway genetics strongly influence serum IgE levels and childhood asthma

Michael Kabesch, Michaela Schedel, David Carr, +4

Journal of Allergy and Clinical Immunology

InflammationAsthmaImmunogeneticsSerum Ige LevelsAllergy +7

NOD1 variation, immunoglobulin E and asthma

Pirro G. Hysi, Michael Kabesch, Miriam F. Moffatt, +13

Human Molecular Genetics

Asthma-associated polymorphisms in 17q21 influence cord blood ORMDL3 and GSDMA gene expression and IL-17 secretion

Anna Lluis, Michaela Schedel, Jing Liu, +5

Journal of Allergy and Clinical Immunology

InflammationAsthmaGsdma Gene ExpressionAsthma-associated PolymorphismsCytokine +6

Unifying Candidate Gene and GWAS Approaches in Asthma

Sven Michel, Liming Liang, Martin Depner, +18

PLoS ONE

AsthmaAsthma Candidate GenesGeneticsGenetic EpidemiologyHuman Polymorphism +14

A signal transducer and activator of transcription 6 haplotype influences the regulation of serum IgE levels

Michaela Schedel, David Carr, Norman Klopp, +8

Journal of Allergy and Clinical Immunology

Serum Ige LevelsImmunogeneticsTranscriptional RegulationAllergyMedicine +12

The role of polymorphisms in ADAM33, a disintegrin and metalloprotease 33, in childhood asthma and lung function in two German populations

Michaela Schedel, Martin Depner, Carola Schoen, +10

Respiratory Research

Polymorphisms related to ORMDL3 are associated with asthma susceptibility, alterations in transcriptional regulation of ORMDL3, and changes in TH2 cytokine levels

Michaela Schedel, Sven Michel, Vincent D. Gaertner, +16

Journal of Allergy and Clinical Immunology

AsthmaInflammationTranscriptional RegulationAllergyInflammatory Lung Disease +9

1,25D3 prevents CD8+Tc2 skewing and asthma development through VDR binding changes to the Cyp11a1 promoter

Michaela Schedel, Yi Jia, Sven Michel, +12

Nature Communications

TBX21 gene variants increase childhood asthma risk in combination with HLX1 variants

Kathrin Suttner, Philip Rosenstiel, Martin Depner, +10

Journal of Allergy and Clinical Immunology

AsthmaTbx21 Gene VariantsImmunogeneticsAllergyGenetics +8

Dysregulation of metabolic pathways in a mouse model of allergic asthma

Kevin Quinn, Michaela Schedel, Yasmeen Nkrumah‐Elie, +6

Allergy