Akifumi Kimura

E5531, a Pure Endotoxin Antagonist of High Potency

William J. Christ, Osamu Asano, Andrea L. C. Robidoux et al. · Science · 1995 · 321 citations

Pharmacotherapy, Viable Escherichia Coli, Drug Resistance +16

Acyl-CoA:cholesterol acyltransferase 1 mediates liver fibrosis by regulating free cholesterol accumulation in hepatic stellate cells

Kengo Tomita, Toshiaki Teratani, Takahiro Suzuki et al. · Journal of Hepatology · 2014 · 90 citations

Hepatic Stellate Cells, Free Cholesterol Accumulation, Pathology +16

Removal of increased circulating CD4+CD25+Foxp3+ regulatory T cells in patients with septic shock using hemoperfusion with polymyxin B-immobilized fibers

Satoshi Ono, Akifumi Kimura, Shuichi Hiraki et al. · Surgery · 2012 · 46 citations

Inflammation, Cell Therapy, Polymyxin B-immobilized Fibers +11

Effects of Neutrophil Elastase Inhibitor on Progression of Acute Lung Injury Following Esophagectomy

Satoshi Ono, Hironori Tsujimoto, Shuichi Hiraki et al. · World Journal of Surgery · 2007 · 35 citations · Full text

Discovery of a potent, metabolically stabilized resorcylic lactone as an anti-inflammatory lead

Hong Du, Tomohiro Matsushima, Mark R. Spyvee et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 28 citations

Medicinal Chemistry, Anti-inflammatory, Biochemistry +9