Seiichi Kobayashi

Self-assembled hydrogel nanoparticle of cholesterol-bearing pullulan as a carrier of protein drugs: Complexation and stabilization of insulin

Kazunari Akiyoshi, Seiichi Kobayashi, Shozo Shichibe et al. · Journal of Controlled Release · 1998 · 434 citations

Pharmacy, Biochemistry, Pharmaceutics +16

E5531, a Pure Endotoxin Antagonist of High Potency

William J. Christ, Osamu Asano, Andrea L. C. Robidoux et al. · Science · 1995 · 323 citations

Veterinary Medicine, Immunology, Microbiology +17

Inhibition of Endotoxin Response by E5564, a Novel Toll-Like Receptor 4-Directed Endotoxin Antagonist

Maureen Mullarkey, Jeffrey Rose, John R. Bristol et al. · Journal of Pharmacology and Experimental Therapeutics · 2003 · 292 citations

Life Sciences, Immunology, Pharmacology +13

Antibodies to β₂‐glycoprotein I and clinical manifestations in patients with systemic lupus erythematosus

Akito Tsutsumi, Eiji Matsuura, Kenji Ichikawa et al. · Arthritis & Rheumatism · 1996 · 200 citations

Life Sciences, Immunology, Autoimmunity +14

Microsatellite polymorphism in heme oxygenase-1 gene promoter is associated with susceptibility to oxidant-induced apoptosis in lymphoblastoid cell lines

Hisao Hirai, Hiroshi Kubo, Mutsuo Yamaya et al. · Blood · 2003 · 164 citations

Life Sciences, Genetics, Molecular Genetics +17