Patrick W.B. Derksen

High sensitivity of BRCA1-deficient mammary tumors to the PARP inhibitor AZD2281 alone and in combination with platinum drugs

Sven Rottenberg, Janneke E. Jaspers, Ariena Kersbergen et al. · Proceedings of the National Academy of Sciences · 2008 · 949 citations · Full text

Medicine, Oncology, Pharmacology +16

Somatic inactivation of E-cadherin and p53 in mice leads to metastatic lobular mammary carcinoma through induction of anoikis resistance and angiogenesis

Patrick W.B. Derksen, Xiaoling Liu, Francis N. Saridin et al. · Cancer Cell · 2006 · 594 citations · Full text

Medicine, Cancer Biology, Oncology +16

Selective Inhibition of BRCA2-Deficient Mammary Tumor Cell Growth by AZD2281 and Cisplatin

Bastiaan Evers, Rinske Drost, Eva Schut et al. · Clinical Cancer Research · 2008 · 334 citations · Full text

Medicine, Oncology, Pharmacology +16

Mesenchymal Stem Cells Induce Resistance to Chemotherapy through the Release of Platinum-Induced Fatty Acids

Jeanine M.L. Roodhart, Laura G.M. Daenen, Edwin C.A. Stigter et al. · Cancer Cell · 2011 · 306 citations · Full text

Medicine, Cell Biology, Oncology +13

Illegitimate WNT signaling promotes proliferation of multiple myeloma cells

Patrick W.B. Derksen, Esther P.M. Tjin, Helen P. Meijer et al. · Proceedings of the National Academy of Sciences · 2004 · 302 citations · Full text

Life Sciences, Cancer Biology, Cell Biology +17