Fiona C. Brown

Molecular patterns of response and treatment failure after frontline venetoclax combinations in older patients with AML

Courtney D. DiNardo, Ing Soo Tiong, Anna Quaglieri et al. · Blood · 2020 · 649 citations · Full text

Medicine, Oncology, Pharmacology +9

DPP8/DPP9 inhibitor-induced pyroptosis for treatment of acute myeloid leukemia

Darren C. Johnson, Cornelius Y. Taabazuing, Marian C. Okondo et al. · Nature Medicine · 2018 · 361 citations · Full text

Medicine, Oncology, Pharmacology +9

Chemotherapy and Venetoclax in Elderly Acute Myeloid Leukemia Trial (CAVEAT): A Phase Ib Dose-Escalation Study of Venetoclax Combined With Modified Intensive Chemotherapy

Chong Chyn Chua, Andrew W. Roberts, John Reynolds et al. · Journal of Clinical Oncology · 2020 · 190 citations

Medicine, Oncology, Pharmacotherapy +17

Intact TP-53 function is essential for sustaining durable responses to BH3-mimetic drugs in leukemias

Rachel Thijssen, Sarah T. Diepstraten, Donia M. Moujalled et al. · Blood · 2021 · 135 citations · Full text

Medicine, Cancer Biology, Oncology +12

Acquired mutations in BAX confer resistance to BH3-mimetic therapy in acute myeloid leukemia

Donia M. Moujalled, Fiona C. Brown, Chong Chyn Chua et al. · Blood · 2022 · 102 citations · Full text

Medicine, Oncology, Pharmacology +16