Lei Guo

The innate immunity protein IFITM3 modulates γ-secretase in Alzheimer’s disease

Ji‐Yeun Hur, Georgia Frost, Xianzhong Wu et al. · Nature · 2020 · 360 citations · Full text

Neurodegenerative Diseases, Alzheimer's Disease, Medicine +8

Molecular subtyping of Alzheimer’s disease using RNA sequencing data reveals novel mechanisms and targets

Ryan Neff, Minghui Wang, Sezen Vatansever et al. · Science Advances · 2021 · 309 citations · Full text

Macrophages in spinal cord injury: Phenotypic and functional change from exposure to myelin debris

Xi Wang, Kai Cao, Xin Sun et al. · Glia · 2014 · 304 citations · Full text

Inflammation, Functional Change, Spinal Cord Injury +14

Microglia and macrophages promote corralling, wound compaction and recovery after spinal cord injury via Plexin-B2

Xiang Zhou, Shalaka Wahane, Marie-Sophie Friedl et al. · Nature Neuroscience · 2020 · 270 citations · Full text

Inflammation, Neuroregeneration, Spinal Cord Injury +10

Transformative Network Modeling of Multi-omics Data Reveals Detailed Circuits, Key Regulators, and Potential Therapeutics for Alzheimer’s Disease

Minghui Wang, Aiqun Li, Michiko Sekiya et al. · Neuron · 2020 · 207 citations · Full text

Neurodegenerative Diseases, Systems Biology, Alzheimer's Disease +13