Lyndon Chie

Glutathione-S-Transferase as a selective inhibitor of oncogenic ras-p21-induced mitogenic signaling through blockade of activation of jun by jun-N-terminal kinase.

A Villafania, Khandaker N. Anwar, Shazia Amar et al. · PubMed · 2000 · 41 citations

Immunology, Cell Death, Oocyte Maturation +18

Functional Interactions of Raf and MEK with Jun-N-Terminal Kinase (JNK) Result in a Positive Feedback Loop on the Oncogenic Ras Signaling Pathway

Victor Adler, Yongxia Qu, Steven J. Smith et al. · Biochemistry · 2005 · 31 citations

Induction of oocyte maturation by jun -N-terminal kinase (JNK) on the oncogenic ras -p21 pathway is dependent on the raf -MEK-MAP kinase signal transduction pathway

Lyndon Chie, Shazia Amar, H F Kung et al. · Cancer Chemotherapy and Pharmacology · 2000 · 25 citations

Developmental Biology, Signal Transduction, Oncogenic Ras +9

Differences in Patterns of Activation of MAP Kinases Induced by Oncogenic ras–p21 and Insulin in Oocytes

Masood Ranginwale, Steven J. Smith, Judy Flom et al. · Experimental Cell Research · 2001 · 19 citations

Signal Transduction, Oncogenic Ras–p21, Cell Regulation +9

Peptides designed from molecular modeling studies of the ras -p21 protein induce phenotypic reversion of a pancreatic carcinoma cell line but have no effect on normal pancreatic acinar cell growth

Mecheal Kanovsky, Josef Michl, Georgia Botzolaki et al. · Cancer Chemotherapy and Pharmacology · 2003 · 16 citations

Pancreatic Cancer, Peptide Therapeutic, Systems Biology +4